Kusalinganika kwa mahomoni kumachitika tikakhala ndi mahomoni ochepa kwambiri kapena ochulukirapo kapena angapo m'thupi lathu.Mahomoni amagwira ntchito yofunika kwambiri pakuwongolera thanzi lathu, ndipo kusalinganika pang'ono kwa mahomoni kungayambitse mavuto ambiri.Izi zili choncho chifukwa mahomoni opangidwa ndi dongosolo la endocrine ndi ofunikira potumiza mauthenga ku ziwalo zosiyanasiyana za thupi ndikuwalangiza zoyenera kuchita ndi nthawi yomwe ayenera kuchita, monga kagayidwe kathu, kuthamanga kwa magazi, kubereka, kuthetsa kupsinjika maganizo, maganizo. , ndi zina zotero. Onse aŵiri amuna ndi akazi amakhala ndi vuto la kusalinganika kwa mahomoni.Azimayi amakhudzidwa ndi kusalinganika kwa progesterone ndi estrogen, pamene amuna amatha kuvutika ndi kusalinganika kwa testosterone.Zizindikiro za kusalinganika kwa mahomoni zimasiyanasiyana malinga ndi mahomoni omwe akhudzidwa, koma izi ndi monga kunenepa, ziphuphu, kuchepa kwa chilakolako chogonana, kuwonda tsitsi, ndi zina zambiri.Kuphatikiza apo, pali mavuto ena azaumoyo omwe angayambitsenso kusagwirizana kwa mahomoni.Matendawa akuphatikizapo polycystic ovary syndrome, shuga, zotupa za endocrine gland, matenda a Addison, hyper kapena hypothyroidism, ndi zina.Dongosolo la endocannabinoid limagwira ntchito pakuwongolera kupanga kwa mahomoni athu.Pali CB1 ndi CB2 zolandilira thupi lonse, mitundu iwiri ya cannabinoid zolandilira.Amatha kumangirira ku cannabinoids mu chomera cha cannabis.Onse a tetrahydrocannabinol (THC) ndi cannabidiol (CBD) amatha kumangirira ku mahomoniwa m'thupi ndikuthandizira kukhazikika kwa dongosolo la endocannabinoid, lomwe limayang'anira mahomoni kudzera m'ntchito zambiri zomwe amathandizira: chilakolako, mimba, Mood, chonde, chitetezo chokwanira komanso chitetezo chokwanira cha homeostasis.Ubale pakati pa njira za endocrine ndi dongosolo la endocannabinoid wakhazikitsidwa ndi kafukufuku."Tikudziwa kuti dongosolo la endocannabinoid limathandizira kuti homeostasis ikhale yabwino.Zimatsimikiziranso kuti matupi athu akugwira ntchito mkati mwa njira zochepetsetsa zogwirira ntchito;otchedwa homeostasis,” anatero Dr. Mooch."ECS imadziwika kuti imayang'anira kupsinjika, malingaliro, chonde, kukula kwa mafupa, kupweteka, chitetezo chamthupi ndi zina zambiri.CBD imalumikizana ndi ma cell endothelial ndi ma receptors ena ambiri m'thupi, "adatero.Pali maphunziro ambiri owonetsa momwe cannabis ingathandizire kuwongolera mahomoni.Maphunzirowa akuwonetsa momwe thupi limachira pambuyo pogwiritsa ntchito CBD kapena chamba ndi THC, chifukwa cannabinoids amathandizira kukonza kuchulukira kapena kuperewera kwa mahomoni akamalumikizana ndi ma neurotransmitters muubongo.
Nawa matenda ena okhudzana ndi mahomoni omwe cannabis amatha kuchiza.
Dysmenorrhea
Amayi mamiliyoni ambiri padziko lonse lapansi amavutika ndi ululu wamsambo.Kaya ndi zowawa pang'ono kapena zofooketsa, cannabinoid CBD ingathandize kuchepetsa ululu wa PMS.Zambiri mwazovuta za msambozi ndi chifukwa chakuti prostaglandin imawonjezeka pamene progesterone imachepa panthawi ya msambo, zomwe zimayambitsa kutupa kwambiri, pamene zimapangitsa kuti amayi azimva kupweteka komanso kuchititsa kuti chiberekero chitseke, kupweteka, ndi vasoconstriction.Kafukufuku wasonyeza kuti CBD ikhoza kuthandizira kuchepetsa ululu ndi kutupa chifukwa cha dysmenorrhea chifukwa imalumikizana ndi ma neurotransmitters.Kuphatikiza apo, amayi omwe ali ndi ululu wosaneneka komanso mutu apeza kuti CBD imathandizira kupweteka.Kafukufuku wina wawonetsa kuti CBD imalepheretsa kupanga COX-2, puloteni yomwe imayambitsa kupanga prostaglandins.M'munsimu mulingo wa COX-2, kupweteka pang'ono, kukokana ndi kutupa kunachitika.
Hormone ya chithokomiro
Chithokomiro ndi dzina la endocrine gland yofunika yomwe ili m'munsi mwa khosi.Gland iyi ndiyofunikira pakuwongolera mahomoni ena ambiri omwe amakhudza ntchito zazikulu zathupi komanso thanzi la mtima, kachulukidwe ka mafupa, komanso kuchuluka kwa metabolic.Komanso, chithokomiro chimagwirizana ndi ubongo, ndipo pamene homeostasis, zonse zimagwira ntchito bwino.Komabe, vuto la chithokomiro likhoza kuchitika pamaso pa hyperthyroidism kapena hypothyroidism, zomwe zingayambitse matenda ena ambiri.Popeza dongosolo la endocannabinoid limathandizanso kuwongolera chithokomiro, kugwiritsa ntchito cannabinoid kungathandize kuthana ndi vuto la chithokomiro.Kafukufuku wowunika ulalo wa CBD ndi matenda a chithokomiro akadali koyambirira, koma zomwe tawona mpaka pano zikulonjeza, kuwonetsa kuti cannabinoid ndiyotetezeka komanso yothandiza pakuwongolera kwake.Kafukufuku mu 2015 adawonetsa kuti chithokomiro ndipamene CB1 ndi CB2 zolandilira zimakhazikika.Izi zimalumikizidwanso ndi kuchepa kwa zotupa za chithokomiro, zomwe zikutanthauza kuti zimatha kuchepetsa chotupa.Palinso maphunziro ena omwe amasonyeza ubwino wa CBD pa thanzi la chithokomiro chifukwa ma CB1 receptors amathandiza kuwongolera mahomoni a chithokomiro T3 ndi T4.
Cortisol
Hormone ya nkhawa ya cortisol ndiyofunikira kutidziwitsa ngati pali ngozi yomwe ikubwera.Nthawi zambiri, makamaka mwa anthu omwe ali ndi PTSD komanso kukhala ndi nkhawa komanso zoopsa, ma cortisol amakhalabe apamwamba.CBD imadziwika kuti imatha kupumula komanso kuthetsa nkhawa.Zimathandizira kukhazika mtima pansi GABA neurotransmitter, yomwe imachepetsa kupsinjika kwamanjenje.CBD imakhudzanso ma cannabinoid receptors omwe ali mu hypothalamus, gawo la ubongo lomwe limalumikizana ndi adrenal glands.Chifukwa cha kuyanjana uku, kupanga kwa cortisol kumachepa, zomwe zimatipangitsa kumasuka.
Nthawi yotumiza: Jul-12-2022