Ubusumbane bwa hormone bubaho mugihe dufite bike cyangwa byinshi cyane mumisemburo imwe cyangwa myinshi mumubiri.Imisemburo igira uruhare runini mugutunganya ubuzima bwacu, kandi ubusumbane buke bwa hormone bushobora gutera ibibazo byinshi.Ni ukubera ko imisemburo ikorwa na sisitemu ya endocrine ari ngombwa mu kohereza ubutumwa mu ngingo zitandukanye z'umubiri no kubagira inama icyo gukora n'igihe bagomba kubikora, nka metabolism muri rusange, umuvuduko w'amaraso, ukwezi kwororoka, gucunga ibibazo, imyitwarire , n'ibindi. Abagabo n'abagore bakunze kwibasirwa na hormone.Abagore barashobora kwibasirwa na progesterone na estrogene, mugihe abagabo bashobora kurwara testosterone.Ibimenyetso biranga imisemburo ya hormone biratandukanye bitewe na hormone yibasiwe, ariko muribi harimo kwiyongera ibiro, acne, kugabanuka kwimibonano mpuzabitsina, kunanura umusatsi, nibindi byinshi.Byongeye kandi, hari ibibazo byubuzima bishobora no gutera imisemburo ya hormone.Izi ndwara zirimo syndrome ya polycystic ovary, diabete, ibibyimba bya endocrine gland, indwara ya Addison, hyper cyangwa hypotherroidism, nibindi byinshi.Sisitemu ya endocannabinoid igira uruhare mukugenzura imisemburo yacu.Hariho umubiri wa CB1 na CB2 umubiri wose, ubwoko bubiri bwurumogi.Bashobora guhambira urumogi mu gihingwa cy'urumogi.Tetrahydrocannabinol (THC) na urumogi (CBD) byombi bishobora guhuza iyi misemburo mu mubiri kandi bigafasha guhagarika sisitemu ya endocannabinoid, igenga imisemburo binyuze mu mirimo myinshi bashyigikira: ubushake bwo kurya, gutwita, Imyifatire, ubudahangarwa, ubudahangarwa ndetse na homeostasis muri rusange.Isano iri hagati yimikorere ya endocrine na sisitemu ya endocannabinoid yashyizweho nubushakashatsi.Ati: "Turabizi ko sisitemu ya endocannabinoid igira uruhare mu kubungabunga homeostasis.Iremeza kandi ko imibiri yacu ikora murwego ruto rwimikorere;ibyo bita homeostasis, ”ibi bikaba byavuzwe na Dr. Mooch.“ECS izwiho kugenga imihangayiko, umwuka, uburumbuke, gukura kw'amagufa, ububabare, imikorere y'umubiri n'ibindi.CBD ikorana na selile endothelia hamwe nizindi nyinshi zakira mu mubiri ”.Hariho ubushakashatsi bwinshi bwerekana uburyo urumogi rushobora gufasha kugenzura imiterere ya hormone.Ubu bushakashatsi bwerekana uburyo umubiri ubona gukira nyuma yo gukoresha CBD cyangwa urumogi hamwe na THC, kuko urumogi rufasha gukosora imisemburo iyo ari yo yose cyangwa ibura iyo ikorana na neurotransmitter mu bwonko.
Hano hari indwara ziterwa na hormone urumogi rushobora kuvura.
Dysmenorrhea
Amamiliyoni y'abagore ku isi barwaye ububabare bw'imihango.Byaba ububabare bworoheje cyangwa butesha umutwe, urumogi CBD rushobora gufasha kugabanya ububabare bwa PMS.Inyinshi murizo ndwara zububabare bwimihango ni ukubera prostaglandine yiyongera mugihe progesterone igabanuka mugihe cyimihango, bigatera umuriro mwinshi, mugihe abagore bumva ububabare bukabije kandi bigatera kwikuramo nyababyeyi, kubabara, na vasoconstriction.Ubushakashatsi bwerekanye ko CBD ishobora gufasha kugabanya ububabare n’umuriro biterwa na dysmenorrhea kuko ikorana na neurotransmitter.Byongeye kandi, abagore bafite ububabare budashira no kubabara umutwe basanze CBD itanga ububabare.Ubundi bushakashatsi bwerekanye ko CBD ibuza neza umusaruro wa COX-2, enzyme itera umusaruro wa prostaglandine.Hasi urwego rwa COX-2, ububabare buke, kubabara no gutwika byabaye.
Umusemburo wa tiroyide
Thyroid ni izina rya glande ikomeye ya endocrine iherereye munsi yijosi.Iyi glande ningirakamaro mugutunganya indi misemburo myinshi igira ingaruka kumikorere ikomeye yumubiri kimwe nubuzima bwumutima, ubwinshi bwamagufwa, nigipimo cya metabolike.Na none, tiroyide ihujwe n'ubwonko, kandi iyo homeostasis, imikorere yose neza.Nyamara, imikorere mibi ya tiroyide irashobora kugaragara imbere ya hyperthyroidism cyangwa hypotherroidism, ibyo nabyo bikaba bishobora gutera ibindi bibazo byinshi byubuzima.Kubera ko sisitemu ya endocannabinoid nayo ifasha kugenzura tiroyide, gukoresha urumogi birashobora gufasha gucunga ibimenyetso byerekana imikorere mibi ya tiroyide.Ubushakashatsi bwasesenguye isano iri hagati ya CBD n'indwara ya tiroyide buracyari mu ntangiriro zayo, ariko ibyo tumaze kubona kugeza ubu biratanga ikizere, byerekana ko urumogi rwose rufite umutekano kandi rufite akamaro mu micungire yarwo.Ubushakashatsi bwakozwe mu 2015 bwerekanye ko tiroyide ariho yakira CB1 na CB2.Ibi kandi bifitanye isano no kugabanya ibibyimba bya tiroyide, bivuze kandi ko bifite ubushobozi bwo kugabanya ibibyimba.Hariho ubundi bushakashatsi bwerekana inyungu za CBD kubuzima bwa tiroyide kuko reseptor ya CB1 ifasha kugenzura imisemburo ya T3 na T4.
Cortisol
Imisemburo ya hormone cortisol ningirakamaro mu kutumenyesha niba hari akaga kegereje.Akenshi, cyane cyane kubantu barwaye PTSD no guhura nibibazo bidakira hamwe nakaga, urugero rwa cortisol rukunda kuba hejuru.CBD izwiho ubushobozi bwo kuruhuka no kugabanya imihangayiko.Ifasha gutuza GABA neurotransmitter, hanyuma igabanya imitekerereze ya sisitemu.CBD ifata kandi reseptor ya urumogi ruherereye muri hypothalamus, igice cyubwonko gihuza na glande ya adrenal.Kubera iyi mikoranire, umusaruro wa cortisol uragabanuka, bidufasha kuruhuka.
Igihe cyo kohereza: Nyakanga-12-2022