Ukungalingani kwama-hormone kwenzeka lapho sinehomoni encane kakhulu noma eningi kakhulu emzimbeni wethu.Amahomoni adlala indima ebaluleke kakhulu ekulawuleni impilo yethu, futhi ukungalingani okuncane kwamahomoni kungabangela izinkinga eziningi.Lokhu kungenxa yokuthi amahomoni akhiqizwa uhlelo lwe-endocrine abalulekile ekuthumeleni imiyalezo ezingxenyeni ezihlukahlukene zomzimba nokuzicebisa ukuthi zenzeni nokuthi kufanele zikwenze nini, njengokugayeka kokudla emzimbeni, umfutho wegazi, umjikelezo wokuzala, ukulawula ukucindezeleka, isimo sengqondo. , njll. Bobabili abesilisa nabesifazane bathambekele ekungalinganini kwama-hormone.Abesifazane basengozini yokungalingani kwe-progesterone ne-estrogen, kuyilapho amadoda ehlushwa ukungalingani kwe-testosterone.Izimpawu zokungalingani kwe-hormone ziyahlukahluka kuye ngokuthi i-hormone ethintekile, kodwa lezi zihlanganisa ukukhuluphala, izinduna, ukuncipha komdlandla wobulili, ukuncipha kwezinwele, nokunye.Ngaphezu kwalokho, kunezinye izinkinga zempilo ezingase ziholele ekungalinganini kwama-hormone.Lezi zifo zihlanganisa i-polycystic ovary syndrome, isifo sikashukela, izimila ze-endocrine gland, isifo sika-Addison, i-hyper noma i-hypothyroidism, nokuningi.Uhlelo lwe-endocannabinoid ludlala indima ekulawuleni ukukhiqizwa kwamahomoni ethu.Kukhona ama-CB1 nama-CB2 receptors kuwo wonke umzimba, izinhlobo ezimbili zama-cannabinoid receptors.Bangakwazi ukubopha kuma-cannabinoids esitshalweni se-cannabis.Kokubili i-tetrahydrocannabinol (THC) kanye ne-cannabidiol (i-CBD) ingabophezela kulawa mahomoni emzimbeni futhi isize ukuzinzisa uhlelo lwe-endocannabinoid, olulawula amahomoni ngemisebenzi eminingi abayisekelayo: isifiso sokudla, ukukhulelwa, iMood, inzalo, ukungatheleleki kanye ne-immune homeostasis.Ukuxhumana phakathi kwezinqubo ze-endocrine nohlelo lwe-endocannabinoid kusungulwe ucwaningo.“Siyazi ukuthi uhlelo lwe-endocannabinoid ludlala indima ekugcineni i-homeostasis.Iphinde iqinisekise ukuthi imizimba yethu isebenza ngaphansi kwezimo eziwumngcingo zokusebenza;okuthiwa yi-homeostasis,” kusho uDkt. Mooch.“I-ECS yaziwa ngokulawula ingcindezi, isimo sengqondo, inzalo, ukukhula kwamathambo, ubuhlungu, ukusebenza kwamasosha omzimba nokunye.I-CBD isebenzisana namaseli endothelial namanye ama-receptors amaningi emzimbeni, ”kusho yena.Kunezifundo eziningi ezikhombisa ukuthi i-cannabis ingasiza kanjani ukulawula ibhalansi ye-hormonal.Lezi zifundo zibhala ukuthi umzimba uthola kanjani ukululama ngemuva kokusebenzisa i-CBD noma i-cannabis nge-THC, njengoba ama-cannabinoids asiza ukulungisa noma yikuphi ukweqisa noma ukushoda kwama-hormone lapho esebenzisana nama-neurotransmitters ebuchosheni.
Nazi ezinye izifo ezihlobene nama-hormone ezingaphathwa yi-cannabis.
Di-ysmenorrhea
Izigidi zabesifazane emhlabeni wonke zihlushwa izinhlungu zokuya esikhathini.Kungakhathaliseki ukuthi ubuhlungu obuncane noma obuqeda amandla, i-cannabinoid CBD ingasiza ekudambiseni ubuhlungu be-PMS.Iningi lalezi zimo ezibuhlungu zokuya esikhathini kungenxa yokuthi i-prostaglandin iyanda kuyilapho i-progesterone yehla ngesikhathi sokuya esikhathini, okubangela ukuvuvukala okwengeziwe, kuyilapho kwenza abesifazane bazizwele kakhulu ebuhlungu futhi kubangele ukufinyela kwesibeletho, amajaqamba, kanye ne-vasoconstriction.Ucwaningo luye lwabonisa ukuthi i-CBD ingasiza ekunciphiseni ubuhlungu nokuvuvukala okubangelwa i-dysmenorrhea ngoba ixhumana nama-neurotransmitters.Ukwengeza, abesifazane abanobuhlungu obungapheli kanye nekhanda elibuhlungu bathole i-CBD ukuhlinzeka ngokukhululeka kobuhlungu.Olunye ucwaningo luye lwabonisa ukuthi i-CBD ivimbela ngempumelelo ukukhiqizwa kwe-COX-2, i-enzyme ebangela ukukhiqizwa kwe-prostaglandin.Lapho izinga le-COX-2 liphansi, ubuhlungu obuncane, ukuminya nokuvuvukala kwenzeka.
I-hormone ye-thyroid
I-thyroid yigama lendlala ebalulekile ye-endocrine etholakala phansi kwentamo.Le ndlala ibalulekile ekulawuleni amanye amahomoni amaningi athinta imisebenzi emikhulu yomzimba kanye nempilo yenhliziyo, ukuminyana kwamathambo, nezinga lokugayeka kokudla.Futhi, indlala yegilo ixhunywe ebuchosheni, futhi lapho i-homeostasis, konke kusebenza kahle.Kodwa-ke, ukungasebenzi kahle kwe-thyroid kungenzeka lapho kukhona i-hyperthyroidism noma i-hypothyroidism, okungaholela kwezinye izinkinga eziningi zempilo.Njengoba uhlelo lwe-endocannabinoid lusiza futhi ukulawula indlala yegilo, ukusetshenziswa kwe-cannabinoid kungasiza ekulawuleni izimpawu zokungasebenzi kahle kwegilo.Ucwaningo oluhlaziya ukuxhumana phakathi kwe-CBD nesifo se-thyroid lusaqala, kodwa esikubonile kuze kube manje kuyethembisa, okubonisa ukuthi le cannabinoid ngempela iphephile futhi iyasebenza ekuphathweni kwayo.Ucwaningo ngo-2015 lwembula ukuthi i-thyroid yilapho i-CB1 ne-CB2 receptors zigxila khona.Lezi futhi zihlotshaniswa nokuncipha kwezimila zegilo, okusho ukuthi inamandla okunciphisa isimila.Kukhona ezinye izifundo ezibonisa izinzuzo ze-CBD zempilo yegilo ngoba ama-CB1 receptors asiza ukulawula i-T3 ne-T4 amahomoni egilo.
Ci-ortisol
I-hormone yokucindezeleka i-cortisol ibalulekile ukuze usazise uma kunengozi ezayo.Ngokuvamile, ikakhulukazi kubantu abane-PTSD kanye nokuchayeka ekucindezelekeni okungapheli kanye nengozi, amazinga e-cortisol avame ukuhlala phezulu.I-CBD yaziwa ngamandla ayo okuphumula nokukhulula ingcindezi.Kuyasiza ukuthulisa i-neurotransmitter ye-GABA, ebese yehlisa ukucindezeleka kwesimiso sezinzwa.I-CBD iphinda ithinte ama-cannabinoid receptors atholakala ku-hypothalamus, ingxenye yobuchopho exhuma nezindlala ze-adrenal.Ngenxa yalokhu kusebenzisana, ukukhiqizwa kwe-cortisol kuncipha, okusivumela ukuba siphumule.
Isikhathi sokuthumela: Jul-12-2022